Posts

FDA encourages CBD clinical research

FDA Encourages Cannabis-Related Clinical Research

This week, the FDA issued draft guidance to encourage cannabis-related clinical research. We love to see news like this, because we’ve been sponsoring and advocating for veterinary CBD research since the early days of the industry. When everyone else was rushing to slap a cute pet label on a bottle of CBD that might (or might not) contain what the label says it contains, we were out there doing the hard work. Meeting with the scientists and veterinarians at Colorado State University’s College of Veterinary Medicine, sponsoring safety trials and and pharmacokinetics research, and helping to launch Phase 2 efficacy trials for epilepsy and arthritis takes a vast amount of resources, but we’ve been committed from the get-go to doing this right.

Clinical research on the benefits of CBD oil for pets is the reason our company exists. We hear so many stories from our customers about the ways that our CBD oil helps their pets, and we think all those stories deserve to be investigated. That’s why we’re launching a foundation to focus exclusively on raising funds for more research. You’ll hear more from us soon about the foundation, so stay tuned. In the meantime, you can read more about our research and all the veterinary clinical trials here.

Stephanie McGrath, DVM works with a St. Bernard during a CBD epiilepsy study
Stephanie McGrath, DVM works with a St. Bernard during a CBD epiilepsy study. Photo credit: CSU

As the CBD industry shifts from a “Wild West” mentality to a more regulated and mature industry, the FDA will play an increasing role. Encouraging clinical research—and offering guidelines—is an important step, and one that we welcome. FDA Principal Deputy Commissioner Amy Abernethy M.D., Ph.D described the FDA’s new guidance in a press release issued by the agency:

“A range of stakeholders have expressed interest in development of drugs that contain cannabis and compounds found in cannabis. Recent legislative changes have also opened new opportunities for cannabis clinical research. As that body of research progresses and grows, the FDA is working to support drug development in this area. It is critical that the FDA continues to do what we can to support the science needed to develop new drugs from cannabis. The FDA believes the drug approval process represents the best way to ensure that safe and effective new medicines, including any drugs that contain cannabis or cannabis-derived compounds, are available to patients in need of appropriate medical therapy. It is critical that the FDA continues to do what we can to support the science needed to develop new drugs from cannabis. The FDA believes the drug approval process represents the best way to ensure that safe and effective new medicines, including any drugs that contain cannabis or cannabis-derived compounds, are available to patients in need of appropriate medical therapy.

FDA In Brief: FDA Issues Draft Guidance to Encourage Cannabis-Related Clinical Research, July 21, 2020. https://www.fda.gov/news-events/fda-brief/fda-brief-fda-issues-draft-guidance-encourage-cannabis-related-clinical-research

Three cheers for more FDA involvement in the CBD industry, more accountability from producers, and most importantly, MORE CLINICAL RESEARCH! This is music to our ears.

Want to try to most rigorously researched and tested CBD oil for your pet? Visit the shop, or reach out to care@petpainfree.com with any questions!

Rottweiler puppy uses CBD

CBD for Puppy Growing Pains

Titan’s upside down puppy grin says it all. He gives ABSC Pure Organic CBD Oil™ two paws up!

Dr. Stephanie McGrath

Dr. Stephanie McGrath Addresses CSU Pueblo

Assessment of Safety, Toxicity, and Pharmacokinetics of Cannabidiol in Healthy Dogs

Have you ever wanted to know more about ABSC and how we came to be involved with clinical trials at CSU? We’re pulling a video out of the archives today to share with you! This short video of Veterinary Neurologist Dr. Stephanie McGrath speaking at a conference at CSU Pueblo in 2017 highlights her work on safety, toxicity, and pharmacokinetics of CBD. During her talk, Dr. McGrath discusses her interest in testing CBD for dogs and her concerns with unregulated and untested CBD products. She needed a safe and pure product to run trials with, and ABSC wanted to support advanced research in the field. It was a match made in heaven, and the rest is history!

CB1 Receptor Chart

The Endocannabinoid System Explained

Introducing our CBD Literacy video education series

Ever wondered about the science behind CBD and its effects on your dog’s body? We know that many of our furry companions who use C.H.O.™ CBD Oil get relief from pain, anxiety, seizures and more. But you may have wondered, “how and why does CBD work?”

Our friend and colleague Sam Stewart, DVM, from Ethos Veterinary Health, has prepared this excellent video to explain the endocannibinoid system. This video is the first in a series–part of our effort to lead the way in veterinary CBD research and education. In this first video, you’ll gain a better understanding of how cannabinoids like CBD affect the brain and nervous system. About halfway through (10:22), Sam gives a great example of how CBD interrupts pain signals in the peripheral nervous system. And at minute 17, you’ll find a great explanation of how CBD binds to receptors and inhibits inflammation. The entire video provides a great overview–in layman’s terms–of the powerful endocannabinoid system.

At ABSC, we’re constantly working to improve and evolve science in the name of providing a better quality of life for our ailing companion animals. Want to learn more? Check out our News and Research Library! And subscribe to our YouTube channel–we’ve got more great educational content to come!

CBD Safetly Trial CSU

Groundbreaking Safety, Toxicity, and Pharmacokinetics Study Published

ABSC Sponsored Safety Study Published in the  Journal of the American Holistic Veterinary Medical Association

We are thrilled to announce that our Phase 1 Clinical Trial: Assessment of Safety, Toxicity, and Pharmacokinetics of Cannabidiol in Healthy Dogs has been successfully completed. Sponsored by ABSC Organics and conducted at Colorado State University’s College of Veterinary Medicine and Biomedical Sciences, the trial studied three different delivery mechanisms in 30 healthy beagles. With results appearing in the Fall 2018 issue of the Journal of the American Holistic Veterinary Medical Association, the study concluded that clinical doses of CBD were well tolerated by all the dogs in the study. This is groundbreaking news in the veterinary field, and represents a major step forward for CBD research and pet wellness.

St. Bernard in CBD Clinical Trial
Dr. Stephanie McGrath with Atticus, a 3-year-old Saint Bernard enrolled in a clinical trial of cannabidiol at Colorado State University’s Veterinary Teaching Hospital (Photo by John Eisele/Colorado State University Photography)

ABSC Organics–The Only Veterinary CBD Company With a Phase 1 Safety Trial

At ABSC we know that it’s easy to make claims, but more important to invest in the research to back up those claims. We care deeply about pets and their well-being. That’s why we’re so proud of the fact that ABSC Pure Organic CBD Oil is the only veterinary CBD product that has undergone a Phase 1 trial to assess safety and toxicity. This trial enables researchers to use our product in Phase 2 trials that will study CBD’s effects on epilepsy, arthritis, and more.